FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  AWM Investment Company, Inc.
2. Date of Event Requiring Statement (Month/Day/Year)
09/29/2021
3. Issuer Name and Ticker or Trading Symbol
Assure Holdings Corp. [IONM]
(Last)
(First)
(Middle)
527 MADISON AVENUE, SUITE 2600
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10022
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 1,562,499 (1) (2)
I (1) (2)
By Limited Partnerships (1) (2)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants 12/01/2020 12/02/2025 Common Stock 1,562,499 (2) (3) (4) $ 3.9 (5) I (2) (3) (4) By Limited Partnerships (2) (3) (4)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
AWM Investment Company, Inc.
527 MADISON AVENUE
SUITE 2600
NEW YORK, NY 10022
    X    

Signatures

Adam Stettner 10/05/2021
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) AWM Investment Company, Inc., a Delaware Corporation (AWM), is the investment adviser to Special Situations Fund III QP, L.P. (SSFQP), Special Situations Cayman Fund, L.P. (Cay), Special Situations Private Equity Fund, L.P. (SSPE), and Special Situations Life Sciences Fund, L.P., (LS and together with SSFQP, Cay, and SSPE, the Funds). As the investment adviser to the Funds, AWM holds sole voting and investment power over 658,134 shares of Common Stock of the Issuer (the Shares) held by SSFQP, 218,257 Shares held by Cay, 312,500 Shares held by SSPE and 373,608 Shares held by LS.
(2) Austin W. Marxe (Marxe), David M. Greenhouse (Greenhouse) and Adam C. Stettner (Stettner) are the controlling principals of AWM. The reporting person disclaims beneficial ownership of the Shares, except to the extent of its pecuniary interest therein. This report shall not be deemed an admission that the reporting person is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.
(3) AWM Investment Company, Inc., a Delaware Corporation (AWM), is the investment adviser to Special Situations Fund III QP, L.P. (SSFQP), Special Situations Cayman Fund, L.P. (Cay), Special Situations Private Equity Fund, L.P. (SSPE), and Special Situations Life Sciences Fund, L.P., (LS and together with SSFQP, Cay, and SSPE, the Funds). As the investment adviser to the Funds, AWM holds sole voting and investment power over 3,290,673 Warrants to purchase 658,134 shares of Common Stock held by SSFQP, 1,091,285 Warrants to purchase 218,257 shares of Common Stock held by Cay, 1,562,500 Warrants to purchase 312,500 shares of Common Stock held by SSPE and 1,868,042 Warrants to purchase 373,608 shares of Common Stock held by LS.
(4) The Warrants described herein may only be exercised to the extent that the total number of Common Shares then beneficially owned does not exceed 9.99% of the outstanding shares.
(5) The exercise price of the warrants reflects a 1 for 5 reverse split effective 9/8/2021.

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